Our Researchers

Here you will find a profile of each of our Centre researchers detailing their research interests, key publications and contact details.

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    Alison Michie

    Molecular Lymphopoiesis
    Institution: University of Glasgow Area of interest:

    Focusing on the molecular events that induce haemopoietic stem cells (HSCs) to commit and differentiate towards the B and T lymphocyte lineages.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Alison Michie

    Leukaemia
    University of Glasgow
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    Alistair Boyer

    Institution: University of Glasgow Area of interest: Teams: Publications:

    Link to Enlighten, University of Glasgow

    Alistair Boyer

    Chemical Biology
    University of Glasgow
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    Andrew Biankin

    Translational Research
    Institution: University of Glasgow Area of interest:

    Research goals are to improve outcomes for individuals with pancreatic cancer through the development of early detection and novel therapeutic strategies based on molecular phenotyping and the delineation and implementation of biomarkers that facilitate clinical decision-making.

    CENTRE LEAD

    Teams: Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Andrew Biankin

    Pancreatic Cancer
    University of Glasgow
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    Andrew Sutherland

    Institution: University of Glasgow Area of interest:

    Research in the Sutherland group focuses on the development and understanding of new organic reactions with particular emphasis on using transition metal catalysis to create new chiral molecules.

    Teams: Publications:

    Link to Enlighten, University of Glasgow

    Andrew Sutherland

    Chemical Biology
    University of Glasgow
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    Anthony Chalmers

    Glioblastoma Therapy
    Institution: University of Glasgow Area of interest:

    Glioblastoma is the commonest and most aggressive primary brain tumour and is often refractory to conventional cancer treatments. The ultimate aim of our research group is to improve outcomes for patients with these tumours by overcoming their inherent resistance to radiotherapy and chemotherapy.

    Teams: Mesothelioma Team Brain Tumours Team Publications:

    Link to Enlighten, University of Glasgow

    Anthony Chalmers

    Brain Tumours, Mesothelioma
    University of Glasgow
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    Antonia Roseweir

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Antonia Roseweir

    Colorectal Cancer
    University of Glasgow
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    Campbell Roxburgh

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Campbell Roxburgh

    Colorectal Cancer
    University of Glasgow
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    Chiara Braconi

    Institution: University of Glasgow Area of interest: Teams: Publications:

    Link to Enlighten, University of Glasgow

    Chiara Braconi

    University of Glasgow
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    Chris Halsey

    Institution: University of Glasgow Area of interest:

    Investigating mechanisms of central nervous system disease in childhood acute lymphoblastic leukaemia (ALL) and ways to reduce treatment related toxicity in this condition.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Chris Halsey

    Leukaemia
    University of Glasgow
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    Colin Steele

    Institution: NHS Greater Glasgow and Clyde Area of interest: Teams: Colorectal Cancer Team Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Colin Steele

    Colorectal Cancer, Pancreatic Cancer
    NHS Greater Glasgow and Clyde
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    Craig Dick

    Histopathology
    Institution: NHS Greater Glasgow and Clyde Area of interest:

    Intrathoracic malignancies including lung cancer and mesothelioma.

    Teams: Mesothelioma Team Publications:

    Link to Enlighten, University of Glasgow

    Craig Dick

    Lung cancer, Mesothelioma
    NHS Greater Glasgow and Clyde
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    Daniel Murphy

    Oncogene-Induced Vulnerabilities
    Institution: CRUK Beatson Institute, University of Glasgow Area of interest:

    The oncogene-induced alterations selectively required by cancer cells to maintain viability.

    Teams: Mesothelioma Team Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Daniel Murphy

    Mesothelioma, Pancreatic Cancer
    CRUK Beatson Institute, University of Glasgow
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    Dave Bryant

    Epithelial polarity
    Institution: CRUK Beatson Institute, University of Glasgow Area of interest:

    Control of cell polarity in prostate cancer, part the role played by ARF GTPases and the cell surface protein Podocalyxin.

    Teams: Prostate Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Dave Bryant

    Prostate Cancer
    CRUK Beatson Institute, University of Glasgow
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    David Chang

    Translational Research
    Institution: University of Glasgow Area of interest:

    The development and implementation of stratified medicine through molecular phenotyping using both tissue- and genomic-based assays.

    Teams: Colorectal Cancer Team Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    David Chang

    Colorectal Cancer, Pancreatic Cancer
    University of Glasgow
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    David France

    Institution: University of Glasgow Area of interest: Teams: Publications:

    Link to Enlighten, University of Glasgow

    David France

    Chemical Biology
    University of Glasgow
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    David Irvine

    Institution: University of Glasgow Area of interest: Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    David Irvine

    Leukaemia
    University of Glasgow
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    David Mansouri

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    David Mansouri

    Colorectal Cancer
    University of Glasgow
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    Donald McMillan

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Donald McMillan

    Colorectal Cancer
    University of Glasgow
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    Ewan Cameron

    Institution: University of Glasgow Area of interest: Teams: Breast Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Ewan Cameron

    Breast Cancer
    University of Glasgow
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    Gaurav Malviya

    Nuclear Imaging
    Institution: CRUK Beatson Institute Area of interest:

    Preclinical PET/MRI imaging of cancer using specific probes that allows non-invasive longitudinal assessment of biological processes, such as tumour metabolism, cell proliferation, angiogenesis, hypoxia and receptor dynamics.

    Teams: Publications:

    See PublicationsList.org

    Gaurav Malviya

    CRUK Beatson Institute
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    Heather Jørgensen

    Chronic Myeloid Leukaemia Therapeutics
    Institution: University of Glasgow Area of interest:

    Studying quiescent leukaemic stem cells in order to find ways to overcome resistance to chemotherapy in CML.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Heather Jørgensen

    Leukaemia
    University of Glasgow
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    Helen Wheadon

    Haemopoietic Stem Cells
    Institution: University of Glasgow Area of interest:

    Study of the developmental pathways involved in normal and aberrant haemopoietic stem cells.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Helen Wheadon

    Leukaemia
    University of Glasgow
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    Hing Leung

    Prostate Cancer Biology, Urological Surgery
    Institution: CRUK Beatson Institute Area of interest:

    The significance of the FGF and ERK5 signalling pathways in prostate cancer.

    Teams: Prostate Cancer Team Publications:

    See Recent Publications

    Hing Leung

    Prostate Cancer
    CRUK Beatson Institute
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    Iain MacPherson

    Institution: CRUK Beatson Institute, University of Glasgow Area of interest:

    Rab-coupling protein (RCP)-mediated receptor trafficking in breast cancer progression.

    Teams: Breast Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Iain MacPherson

    Breast Cancer
    CRUK Beatson Institute, University of Glasgow
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    Imran Ahmad

    Bladder cancer, Prostate cancer, Urology
    Institution: CRUK Beatson Institute, University of Glasgow Area of interest:

    Understanding how aberrant signalling drives both bladder and prostate carcinogenesis.

    Teams: Prostate Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Imran Ahmad

    Prostate Cancer
    CRUK Beatson Institute, University of Glasgow
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    James Park

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    James Park

    Colorectal Cancer
    University of Glasgow
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    Janet Graham

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Janet Graham

    Colorectal Cancer
    University of Glasgow
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    Jeff Evans

    Translational Cancer Therapeutics
    Institution: CRUK Beatson Institute, University of Glasgow Area of interest:

    Using transgenic models of pancreatic cancer to  determine how potential anti-cancer agents might best be evaluated in subsequent clinical trials.

    CENTRE LEAD

    Teams: Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Jeff Evans

    Pancreatic Cancer
    CRUK Beatson Institute, University of Glasgow
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    Jen Morton

    Preclinical Trials
    Institution: CRUK Beatson Institute Area of interest:

    Our research focuses mainly on:
    (a) Investigating the importance of mutations found in human pancreatic tumours using mouse models.
    (b) Profiling different genetic subsets of pancreatic cancer to better understand the disease and identify specific targets for therapy.
    (c) Preclinical trials of targeted therapies in clinically and genetically relevant pancreatic cancer mouse models.

    Teams: Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Jen Morton

    Pancreatic Cancer
    CRUK Beatson Institute
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    Jim Norman

    Integrin Cell Biology
    Institution: CRUK Beatson Institute Area of interest:

    The contribution of Rab-regulated integrin trafficking to cancer cell migration.

    Teams: Breast Cancer Team Publications:

    See Recent Publications

    Jim Norman

    Breast Cancer
    CRUK Beatson Institute
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    Joanna Morris

    Veterinary Oncology
    Institution: University of Glasgow Area of interest:

    Mammary gland development of the mouse as a model system for mammary neoplasia.

    Teams: Breast Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Joanna Morris

    Breast Cancer
    University of Glasgow
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    Joanne Edwards

    Translational Cell Signalling‌
    Institution: University of Glasgow Area of interest:

    Investigation of signal transduction mechanisms associated with the development and progression of breast, colorectal, renal and prostate cancer.

    Teams: Colorectal Cancer Team Prostate Cancer Team Breast Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Joanne Edwards

    Breast Cancer, Colorectal Cancer, Prostate Cancer
    University of Glasgow
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    Joëlle Prunet

    School of Chemistry
    Institution: University of Glasgow Area of interest:

    The main research interest of the Prunet group is the synthesis of biologically active natural products, especially anticancer agents, and the development of new synthetic methodologies in organic chemistry. We are also working on new methods for conjugating small-molecule drugs with biocompatible polymers for drug delivery.

    Teams: Publications:

    List of publications (ResearcherID)

    Joëlle Prunet

    Chemical Biology
    University of Glasgow
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    John Le Quesne

    Institution: University of Glasgow Area of interest: Teams: Mesothelioma Team Publications:

    Link to PubMed

    John Le Quesne

    Lung cancer, Mesothelioma
    University of Glasgow
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    Julia Cordero

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Julia Cordero

    Colorectal Cancer
    University of Glasgow
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    Justin Bower

    Chemistry
    Institution: CRUK Beatson Institute Area of interest: Teams: Publications:

    See Profile for Recent Publications

    Justin Bower

    Chemical Biology
    CRUK Beatson Institute
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    Karen Blyth

    Transgenic Models
    Institution: CRUK Beatson Institute Area of interest:

    The role of RUNX2 in metastatic breast and prostate cancer.

    Teams: Breast Cancer Team Publications:

    See Profile for Recent Publications

    Karen Blyth

    Breast Cancer
    CRUK Beatson Institute
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    Karen Keeshan

    Paediatric and Adult Acute Leukaemias
    Institution: University of Glasgow Area of interest:

    The study of normal and malignant haematopoiesis.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Karen Keeshan

    Leukaemia
    University of Glasgow
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    Karin Oien

    Systems Pathology of Cancer
    Institution: University of Glasgow Area of interest:

    Pathology of gastro-intestinal and liver disease, especially cancer.

    Teams: Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Karin Oien

    Pancreatic Cancer
    University of Glasgow
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    Kevin Blyth

    Pleural Disease, Pulmonology, Respiratory Medicine
    Institution: NHS Greater Glasgow and Clyde, Pleural Disease Unit Queen Elizabeth University Hospital Area of interest:

    Translational research focused on novel blood, imaging and physical biomarkers of pleural malignancy, particularly Mesothelioma, and Lung Cancer. Our imaging research is centred around Magnetic Resonance Imaging. Clinical trial portfolio includes studies in diagnostics, imaging, intra-pleural therapy and pleurodesis. Additional areas of interest include Interventional Pulmonology.

    Teams: Mesothelioma Team Publications:

    Link to PubMed

    Kevin Blyth

    Lung cancer, Mesothelioma
    NHS Greater Glasgow and Clyde, Pleural Disease Unit Queen Elizabeth University Hospital
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    Laura Machesky

    Invasion and Metastasis, Migration
    Institution: CRUK Beatson Institute Area of interest:

    The control and mechanisms of actin assembly in various normal and cancer cells.

    Teams: Pancreatic Cancer Team Breast Cancer Team Publications:

    See Profile for Recent Publications

    Laura Machesky

    Breast Cancer, Pancreatic Cancer
    CRUK Beatson Institute
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    Mhairi Copland

    Leukaemia Stem Cell Self-Renewal
    Institution: University of Glasgow Area of interest:

    The abnormalities of stem cell self-renewal and bone marrow microenvironment that develop in myeloid leukaemias.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Mhairi Copland

    Leukaemia
    University of Glasgow
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    Nigel Jamieson

    Surgery
    Institution: University of Glasgow Area of interest:

    Upper GI surgery and pancreaticobiliary disease.

    Teams: Pancreatic Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Nigel Jamieson

    Pancreatic Cancer
    University of Glasgow
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    Owen Sansom

    Colorectal Cancer and Wnt Signalling
    Institution: CRUK Beatson Institute Area of interest:

    Use of novel inducible models of intestinal tumourigenesis to study the functions of specific tumour suppressor genes.

    CENTRE LEAD

    Teams: Colorectal Cancer Team Prostate Cancer Team Pancreatic Cancer Team Publications:

    See Profile for Recent Publications

    Owen Sansom

    Colorectal Cancer, Pancreatic Cancer, Prostate Cancer
    CRUK Beatson Institute
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    Paul Horgan

    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Paul Horgan

    Colorectal Cancer
    University of Glasgow
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    Peter Bailey

    Cancer Systems Biology
    Institution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Peter Bailey

    Colorectal Cancer
    University of Glasgow
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    Richard Hartley

    Chemical Biology
    Institution: University of Glasgow Area of interest:

    We develop mitochondria-targeted probes for understanding the role of this metabolic and signalling hub in cancer. The probes include sensors, fluorophores and photo-activated and ROS-activated prodrugs.

    Teams: Publications:

    Link to ORCID

    Richard Hartley

    Chemical Biology
    University of Glasgow
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    Rob Jones

    Clinical Trials
    Institution: University of Glasgow Area of interest:

    Optimising the use of chemotherapy in prostate cancer.

    Teams: Prostate Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Rob Jones

    Clinical Trials, Prostate Cancer
    University of Glasgow
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    Rob Liskamp

    Chemical Biology, Medicinal Chemistry
    Institution: University of Glasgow Area of interest:

    Research in the Liskamp group is directed towards the creation of molecules that can be used to obtain insights into diseases such as infections and cancer, which may also lead to new approaches for their treatment.

    Teams: Publications:

    ResearcherID

    Rob Liskamp

    Chemical Biology
    University of Glasgow
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    Ross Cagan

    Institution: University of Glasgow Area of interest: Teams: Publications:

    Link to Enlighten, University of Glasgow

    Ross Cagan

    University of Glasgow
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    Sally Pimlott

    Radiopharmaceuticals
    Institution: University of Glasgow Area of interest:

    The development and utility of novel PET/SPECT radiopharmaceuticals in both clinical and preclinical research studies.

    Teams: Publications:

    Link to Enlighten, University of Glasgow

    Sally Pimlott

    University of Glasgow
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    Sara Zanivan

    Angiogenesis, Proteomics
    Institution: CRUK Beatson Institute Area of interest:

    Using state-of-the-art mass spectrometry and quantitative proteomics to study the complex molecular mechanisms regulating endothelial cells during angiogenesis.

    Teams: Breast Cancer Team Publications:

    See Profile for Recent Publications

    Sara Zanivan

    Breast Cancer
    CRUK Beatson Institute
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    Seth Coffelt

    Immune Cells, Metastasis
    Institution: CRUK Beatson Institute, University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:

    See Profile for Recent Publications

    Seth Coffelt

    Colorectal Cancer
    CRUK Beatson Institute, University of Glasgow
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    Stephen Clark

    Institution: University of Glasgow Area of interest: Teams: Publications:

    Link to Enlighten, University of Glasgow

    Stephen Clark

    Chemical Biology
    University of Glasgow
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    Torsten Stein

    Mammary Gland Morphogenesis & Breast Cancer
    Institution: University of Glasgow Area of interest:

    The molecular and cellular changes that occur during mammary gland development and how these are deregulated in breast cancer.

    Teams: Breast Cancer Team Publications:

    Link to Enlighten, University of Glasgow

    Torsten Stein

    Breast Cancer
    University of Glasgow
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    Vignir Helgason

    Leukaemia & Autophagy Therapeutics
    Institution: University of Glasgow Area of interest:

    The role of autophagy in disease persistence and drug resistance in CML.

    Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Vignir Helgason

    Leukaemia
    University of Glasgow
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    Xu Huang

    Institution: University of Glasgow Area of interest: Teams: Leukaemias Team Publications:

    Link to Enlighten, University of Glasgow

    Xu Huang

    Leukaemia
    University of Glasgow