Here you will find a profile of each of our Centre researchers detailing their research interests, key publications and contact details.
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closeInstitution: University of Glasgow Area of interest:
Focusing on the molecular events that induce haemopoietic stem cells (HSCs) to commit and differentiate towards the B and T lymphocyte lineages.
Teams: Leukaemias Team Publications:PreviousAlison Michie
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Chemical Biology Team Publications:Previous
Alistair Boyer
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Research interests are in the area of organic synthesis and methodology, particularly in the area of catalysis.
Teams: Chemical Biology Team Publications:PreviousAllan Watson
Chemical BiologyUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
Research goals are to improve outcomes for individuals with pancreatic cancer through the development of early detection and novel therapeutic strategies based on molecular phenotyping and the delineation and implementation of biomarkers that facilitate clinical decision-making.
CENTRE LEAD
Teams: Colorectal Cancer Team Pancreatic Cancer Team Publications:PreviousAndrew Biankin
Colorectal Cancer, Pancreatic CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Research in the Sutherland group focuses on the development and understanding of new organic reactions with particular emphasis on using transition metal catalysis to create new chiral molecules.
Teams: Chemical Biology Team Publications:PreviousAndrew Sutherland
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
The role of the inhibitory kappaB kinases (IKKs) in the regulation of both Nuclear Factor kappaB (NFkappaB)-dependent and -independent transcription in mediating inflammatory-based responses relevant to infection, regulation of immunity, cardiovascular disease and cancer.
Teams: Breast Cancer Team Publications:PreviousAndy Paul
Breast CancerUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
Glioblastoma is the commonest and most aggressive primary brain tumour and is often refractory to conventional cancer treatments. The ultimate aim of our research group is to improve outcomes for patients with these tumours by overcoming their inherent resistance to radiotherapy and chemotherapy.
Teams: Mesothelioma Team Brain Tumours Team Publications:PreviousAnthony Chalmers
Brain Tumours, MesotheliomaUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Antonia Roseweir
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Drug discovery, molecular structure simulation, machine learning and prediction, data analysis, and web-enabled science and collaboration tools.
Teams: Chemical Biology Team Publications:PreviousBlair Johnston
Chemical BiologyUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Campbell Roxburgh
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Investigating mechanisms of central nervous system disease in childhood acute lymphoblastic leukaemia (ALL) and ways to reduce treatment related toxicity in this condition.
Teams: Leukaemias Team Publications:PreviousChris Halsey
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
- Design and development of novel tumour-targeted anti-cancer nanomedicines
- Design and development of novel nanomedicines able to reach the brain after intravenous administration, with the ultimate aim to facilitate drug and gene delivery to brain tumours
Teams: Prostate Cancer Team Brain Tumours Team Publications:Link to publications
PreviousChristine Dufès
Brain Tumours, Prostate CancerUniversity of Strathclyde -
closeInstitution: University of Strathclyde Area of interest: Teams: Chemical Biology Team Publications:Previous
Colin Gibson
Chemical BiologyUniversity of Strathclyde -
closeInstitution: NHS Greater Glasgow and Clyde Area of interest: Teams: Colorectal Cancer Team Pancreatic Cancer Team Publications:Previous
Colin Steele
Colorectal Cancer, Pancreatic CancerNHS Greater Glasgow and Clyde -
closeInstitution: NHS Greater Glasgow and Clyde Area of interest:
Intrathoracic malignancies including lung cancer and mesothelioma.
Teams: Mesothelioma Team Publications:PreviousCraig Dick
Lung cancer, MesotheliomaNHS Greater Glasgow and Clyde -
closeInstitution: University of Strathclyde Area of interest:
Programmes centred around hit and lead identification on disease targets and mechanisms, particularly in diseases of ageing.
Teams: Chemical Biology Team Publications:PreviousCraig Jamieson
Chemical BiologyUniversity of Strathclyde -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
The oncogene-induced alterations selectively required by cancer cells to maintain viability.
Teams: Mesothelioma Team Pancreatic Cancer Team Publications:PreviousDaniel Murphy
Mesothelioma, Pancreatic CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
Control of cell polarity in prostate cancer, part the role played by ARF GTPases and the cell surface protein Podocalyxin.
Teams: Prostate Cancer Team Publications:PreviousDave Bryant
Prostate CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: University of Glasgow Area of interest:
The development and implementation of stratified medicine through molecular phenotyping using both tissue- and genomic-based assays.
Teams: Colorectal Cancer Team Pancreatic Cancer Team Publications:PreviousDavid Chang
Colorectal Cancer, Pancreatic CancerUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
IGFBP-5, which is highly expressed during development and plays a fundamental role in epithelial-mesenchymal interactions in the embryo.
Teams: Breast Cancer Team Publications:PreviousDavid Flint
Breast CancerUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest: Teams: Chemical Biology Team Publications:Previous
David France
Chemical BiologyUniversity of Glasgow -
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David Irvine
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
David Mansouri
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Donnie McMillan
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Regulation of autophagy by the mTORC1-ULK pathway.
Teams: Breast Cancer Team Publications:PreviousEdmond Chan
Breast CancerUniversity of Strathclyde -
closeInstitution: CRUK Beatson Institute Area of interest:
Facilitating the translation of existing cancer research into cancer treatments, and enhancing the efficacy of existing cancer drugs, potentially through a combinatorial therapeutic approach.
Teams: Breast Cancer Team Publications:PreviousEmma Shanks
Breast CancerCRUK Beatson Institute -
closeInstitution: University of Glasgow Area of interest: Teams: Breast Cancer Team Publications:Previous
Ewan Cameron
Breast CancerUniversity of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest:
Preclinical PET/MRI imaging of cancer using specific probes that allows non-invasive longitudinal assessment of biological processes, such as tumour metabolism, cell proliferation, angiogenesis, hypoxia and receptor dynamics.
Teams: Publications:PreviousGaurav Malviya
CRUK Beatson Institute -
closeInstitution: University of Strathclyde Area of interest:
The chemistry and biology of nucleotides, nucleic acids and nucleic acid binding molecules.
Teams: Chemical Biology Team Publications:PreviousGlenn Burley
Chemical BiologyUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
Studying quiescent leukaemic stem cells in order to find ways to overcome resistance to chemotherapy in CML.
Teams: Leukaemias Team Publications:PreviousHeather Jørgensen
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Study of the developmental pathways involved in normal and aberrant haemopoietic stem cells.
Teams: Leukaemias Team Publications:PreviousHelen Wheadon
LeukaemiaUniversity of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest:
The significance of the FGF and ERK5 signalling pathways in prostate cancer.
Teams: Prostate Cancer Team Publications:PreviousHing Leung
Prostate CancerCRUK Beatson Institute -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
Rab-coupling protein (RCP)-mediated receptor trafficking in breast cancer progression.
Teams: Breast Cancer Team Publications:PreviousIain MacPherson
Breast CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Understanding how aberrant signalling drives both bladder and prostate carcinogenesis.
Teams: Prostate Cancer Team Publications:Rajan, P. et al. (2014) Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy. European Urology, 66(1), pp. 32-39.
Stockley, J., Villasevil, M. E. M., Nixon, C., Ahmad, I., Leung, H., and Rajan, P. (2014) The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer. RNA Biology, 11(6), pp. 1-11.
PreviousImran Ahmad
Prostate CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
James Park
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Janet Graham
Colorectal CancerUniversity of Glasgow -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
Using transgenic models of pancreatic cancer to determine how potential anti-cancer agents might best be evaluated in subsequent clinical trials.
CENTRE LEAD
Teams: Pancreatic Cancer Team Publications:PreviousJeff Evans
Pancreatic CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest:
Our research focuses mainly on:
Teams: Pancreatic Cancer Team Publications:
(a) Investigating the importance of mutations found in human pancreatic tumours using mouse models.
(b) Profiling different genetic subsets of pancreatic cancer to better understand the disease and identify specific targets for therapy.
(c) Preclinical trials of targeted therapies in clinically and genetically relevant pancreatic cancer mouse models.PreviousJen Morton
Pancreatic CancerCRUK Beatson Institute -
closeInstitution: CRUK Beatson Institute Area of interest:
The contribution of Rab-regulated integrin trafficking to cancer cell migration.
Teams: Breast Cancer Team Publications:PreviousJim Norman
Breast CancerCRUK Beatson Institute -
closeInstitution: University of Glasgow Area of interest:
Mammary gland development of the mouse as a model system for mammary neoplasia.
Teams: Breast Cancer Team Publications:PreviousJoanna Morris
Breast CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Investigation of signal transduction mechanisms associated with the development and progression of breast, colorectal, renal and prostate cancer.
Teams: Colorectal Cancer Team Prostate Cancer Team Breast Cancer Team Publications:PreviousJoanne Edwards
Breast Cancer, Colorectal Cancer, Prostate CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
The main research interest of the Prunet group is the synthesis of biologically active natural products, especially anticancer agents, and the development of new synthetic methodologies in organic chemistry. We are also working on new methods for conjugating small-molecule drugs with biocompatible polymers for drug delivery.
Teams: Chemical Biology Team Publications:List of publications (ResearcherID)
PreviousJoëlle Prunet
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest: Teams: Chemical Biology Team Publications:Previous
Jonathan Percy
Chemical BiologyUniversity of Strathclyde -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
Targeting cancer-specific metabolic alterations.
Teams: Pancreatic Cancer Team Publications:PreviousJurre Kamphorst
Pancreatic CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest: Teams: Chemical Biology Team Publications:Previous
Justin Bower
Chemical BiologyCRUK Beatson Institute -
closeInstitution: CRUK Beatson Institute Area of interest:
The role of RUNX2 in metastatic breast and prostate cancer.
Teams: Breast Cancer Team Publications:PreviousKaren Blyth
Breast CancerCRUK Beatson Institute -
closeInstitution: University of Glasgow Area of interest:
The study of normal and malignant haematopoiesis.
Teams: Leukaemias Team Publications:PreviousKaren Keeshan
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Pathology of gastro-intestinal and liver disease, especially cancer.
Teams: Pancreatic Cancer Team Publications:PreviousKarin Oien
Pancreatic CancerUniversity of Glasgow -
closeInstitution: NHS Greater Glasgow and Clyde, Pleural Disease Unit Queen Elizabeth University Hospital Area of interest:
Translational research focused on novel blood, imaging and physical biomarkers of pleural malignancy, particularly Mesothelioma, and Lung Cancer. Our imaging research is centred around Magnetic Resonance Imaging. Clinical trial portfolio includes studies in diagnostics, imaging, intra-pleural therapy and pleurodesis. Additional areas of interest include Interventional Pulmonology.
Teams: Mesothelioma Team Publications:Link to PubMed
PreviousKevin Blyth
Lung cancer, MesotheliomaNHS Greater Glasgow and Clyde, Pleural Disease Unit Queen Elizabeth University Hospital -
closeInstitution: CRUK Beatson Institute Area of interest:
The control and mechanisms of actin assembly in various normal and cancer cells.
Teams: Pancreatic Cancer Team Breast Cancer Team Publications:PreviousLaura Machesky
Breast Cancer, Pancreatic CancerCRUK Beatson Institute -
closeInstitution: University of Strathclyde Area of interest: Teams: Chemical Biology Team Publications:Previous
Mark Dufton
Chemical BiologyUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
The abnormalities of stem cell self-renewal and bone marrow microenvironment that develop in myeloid leukaemias.
Teams: Leukaemias Team Publications:PreviousMhairi Copland
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Research within the group is split into two distinct areas. The development of practical synthetic methodology and the preparation of tool compounds of biological relevance. Our approach to discovery in each of these areas is driven by mechanistic knowledge and understanding.
Teams: Chemical Biology Team Publications:PreviousNick Tomkinson
Chemical BiologyUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
Upper GI surgery and pancreaticobiliary disease.
Teams: Pancreatic Cancer Team Publications:PreviousNigel Jamieson
Pancreatic CancerUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
The molecular mechanisms by which lysolipid receptors regulate cell biology.
Teams: Breast Cancer Team Publications:PreviousNigel Pyne
Breast CancerUniversity of Strathclyde -
closeInstitution: CRUK Beatson Institute Area of interest:
Use of novel inducible models of intestinal tumourigenesis to study the functions of specific tumour suppressor genes.
CENTRE LEAD
Teams: Colorectal Cancer Team Prostate Cancer Team Pancreatic Cancer Team Publications:PreviousOwen Sansom
Colorectal Cancer, Pancreatic Cancer, Prostate CancerCRUK Beatson Institute -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Paul Horgan
Colorectal CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Peter Bailey
Colorectal CancerUniversity of Glasgow -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest:
The Adams lab is interested in the epigenetics of ageing and cancer. In particular, we are interested in age-associated epigenetic changes that predispose to cancer.
Teams: Leukaemias Team Publications:PreviousPeter D Adams
Intestinal/colon cancer, Leukaemia, MelanomaCRUK Beatson Institute, University of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest: Teams: Prostate Cancer Team Publications:Previous
Rachana Patel
Prostate CancerCRUK Beatson Institute -
closeInstitution: University of Glasgow Area of interest:
We develop mitochondria-targeted probes for understanding the role of this metabolic and signalling hub in cancer. The probes include sensors, fluorophores and photo-activated and ROS-activated prodrugs.
Teams: Chemical Biology Team Publications:PreviousRichard Hartley
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Optimising the use of chemotherapy in prostate cancer.
Teams: Clinical Trials Team Prostate Cancer Team Publications:PreviousRob Jones
Clinical Trials, Prostate CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
Research in the Liskamp group is directed towards the creation of molecules that can be used to obtain insights into diseases such as infections and cancer, which may also lead to new approaches for their treatment.
Teams: Chemical Biology Team Publications:PreviousRob Liskamp
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Pharmacology of drugs in cancer.
Teams: Prostate Cancer Team Publications:See Publications
PreviousRobin Plevin
Prostate CancerUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
The development and utility of novel PET/SPECT radiopharmaceuticals in both clinical and preclinical research studies.
Teams: Publications:PreviousSally Pimlott
University of Glasgow -
closeInstitution: CRUK Beatson Institute Area of interest:
Using state-of-the-art mass spectrometry and quantitative proteomics to study the complex molecular mechanisms regulating endothelial cells during angiogenesis.
Teams: Breast Cancer Team Publications:Patella F, Schug ZT, Persi E, Neilson LJ, Erami Z, Avanzato D, Maione F, Hernandez-Fernaud JR, Mackay G, Zheng L, Reid S, Frezza C, Giraudo E, Fiorio Pla A, Anderson K, Ruppin E, Gottlieb E, Zanivan S. Proteomics-based metabolic modelling reveals that fatty acid oxidation controls endothelial cell permeability. Mol Cell Proteomics 14: 621-34, 2015
van den Biggelaar M, Hernández-Fernaud JR, van den Eshof BL, Neilson LJ, Meijer AB, Mertens K, Zanivan S. Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells. Blood 123: e22-36, 2014
PreviousSara Zanivan
Breast CancerCRUK Beatson Institute -
closeInstitution: CRUK Beatson Institute, University of Glasgow Area of interest: Teams: Colorectal Cancer Team Publications:Previous
Seth Coffelt
Colorectal CancerCRUK Beatson Institute, University of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
Cancer drug discovery, in particular to identify small molecule inhibitors for the treatment of prostate cancer.
Teams: Chemical Biology Team Prostate Cancer Team Publications:PreviousSimon Mackay
Chemical Biology, Prostate CancerUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest: Teams: Chemical Biology Team Publications:Previous
Stephen Clark
Chemical BiologyUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest:
The molecular mechanisms by which sphingosine 1-phosphate affects cell function in health and disease.
Teams: Breast Cancer Team Publications:See Selected Publications
PreviousSusan Pyne
Breast CancerUniversity of Strathclyde -
closeInstitution: University of Glasgow Area of interest:
The molecular and cellular changes that occur during mammary gland development and how these are deregulated in breast cancer.
Teams: Breast Cancer Team Publications:PreviousTorsten Stein
Breast CancerUniversity of Glasgow -
closeInstitution: University of Glasgow Area of interest:
The role of autophagy in disease persistence and drug resistance in CML.
Teams: Leukaemias Team Publications:PreviousVignir Helgason
LeukaemiaUniversity of Glasgow -
closeInstitution: University of Strathclyde Area of interest: Teams: Chemical Biology Team Publications:Previous
William Kerr
Chemical BiologyUniversity of Strathclyde -
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Xu Huang
LeukaemiaUniversity of Glasgow